| Microliters (µL) | Megaliters (ML) |
|---|---|
| 1 Microliter | 1 × 10-12 ML |
| 2 Microliters | 2 × 10-12 ML |
| 3 Microliters | 3 × 10-12 ML |
| 4 Microliters | 4 × 10-12 ML |
| 5 Microliters | 5 × 10-12 ML |
| 10 Microliters | 1 × 10-11 ML |
| 20 Microliters | 2 × 10-11 ML |
| 25 Microliters | 2.5 × 10-11 ML |
| 50 Microliters | 5 × 10-11 ML |
| 100 Microliters | 1 × 10-10 ML |
| Reference | Microliters (µL) | Megaliters (ML) |
|---|---|---|
| A teaspoon | 5000 µL | 0.000000005 ML |
| A can of soft drink | 330000 µL | 0.00000033 ML |
| A wine bottle | 750000 µL | 0.00000075 ML |
| A bathtub | 150000000 µL | 0.00015 ML |
| An Olympic swimming pool | 2.5 × 1012 µL | 2.5 ML |
The microlitre is a unit of volume equal to one millionth of a litre, written µL. It is exactly one cubic millimetre. It is the working unit of the molecular biology laboratory and of clinical haematology, and almost every quantity in modern biological science that is not a mass or a concentration is a number of microlitres.
Pipetting is what defines it in practice. Adjustable micropipettes are named after their maximum volume in microlitres, so a bench holds instruments of 2, 20, 200 and 1000, and a researcher's day consists largely of moving microlitres from one tube to another. A polymerase chain reaction is typically assembled in twenty to fifty microlitres, and a whole experiment may use less liquid than a teaspoon holds.
Blood counts are reported against it. White cells number between four thousand and eleven thousand per microlitre in a healthy adult, platelets between a hundred and fifty thousand and four hundred thousand, and red cells about five million. Those reference ranges are among the most widely used numbers in medicine, and all of them are counts within a cube one millimetre on a side.
Diagnostics has driven the volumes down. A modern blood glucose meter needs about half a microlitre of blood, which is why a finger-prick sample is enough where an earlier generation of instruments needed a syringe. Point-of-care analysers, lateral flow tests and microfluidic cartridges are all designed around the smallest sample a patient can be asked to give.
Analytical chemistry uses the same scale. Injection volumes in liquid chromatography run from one to twenty microlitres, gas chromatography uses one or less, and mass spectrometry samples are prepared in tens. Because the analytical signal depends on the amount injected, the accuracy of a microlitre-scale measurement sets the accuracy of the whole result.
The identity with the cubic millimetre is a genuine convenience. Haematology once reported cell counts per cubic millimetre and now reports them per microlitre, and the numbers did not change at all, because the two units are the same. That is a rare case of a unit change in medicine that required no re-education and produced no errors.
One microlitre equals 1 cubic millimetre, 0.001 millilitres, 0.000001 litres, or about 0.0000338 US fluid ounces.
The megalitre is a unit of volume equal to one million litres, or one thousand cubic metres. Its symbol is ML. It is the working unit of water management: irrigation entitlements, treatment works capacity, farm dams and the trading of water rights are all counted in megalitres, because the quantities involved are far too large for litres and awkwardly small for cubic kilometres.
Australia has made the most of it. Irrigation water in the Murray-Darling Basin is held as entitlements measured in megalitres, seasonal allocations are announced as a percentage of those entitlements, and the resulting rights are traded on an open market where prices are quoted in dollars per megalitre. That market is among the largest of its kind in the world, and every price in it is a price per million litres.
British water utilities use it for throughput. A treatment works is rated in megalitres per day, distribution zones are balanced in the same unit, and leakage is reported as megalitres lost daily across a network. Because a large city consumes several hundred megalitres a day, the unit keeps national and regional figures in three or four digits rather than in unreadable strings of zeros.
A familiar object fixes the scale. An Olympic swimming pool of fifty metres by twenty-five, filled to two metres, holds 2500 cubic metres, which is two and a half megalitres. Journalism uses that comparison constantly for reservoir levels and flood volumes, and it works precisely because the pool and the unit are within a factor of three of each other.
On farms the unit describes storage. An Australian farm dam might hold anything from five to fifty megalitres, an on-farm irrigation season is planned in megalitres per hectare, and evaporation losses from open storage are estimated the same way. Sewage treatment, industrial process water and mine site water balances all follow.
Its one hazard is typographic. In the correct symbols, mL is a millilitre and ML is a megalitre, and the two differ by a factor of a thousand million. A document that is careless about capitals can therefore turn a laboratory volume into a reservoir, which is why water and clinical writing both insist on the case being right.
One megalitre equals 1,000,000 litres, 1000 cubic metres, about 264,172 US gallons, or about 220,000 imperial gallons.