| Microliters (µL) | Milliliters (mL) |
|---|---|
| 1 Microliter | 0.001 mL |
| 2 Microliters | 0.002 mL |
| 3 Microliters | 0.003 mL |
| 4 Microliters | 0.004 mL |
| 5 Microliters | 0.005 mL |
| 10 Microliters | 0.01 mL |
| 20 Microliters | 0.02 mL |
| 25 Microliters | 0.025 mL |
| 50 Microliters | 0.05 mL |
| 100 Microliters | 0.1 mL |
| Reference | Microliters (µL) | Milliliters (mL) |
|---|---|---|
| A teaspoon | 5000 µL | 5 mL |
| A can of soft drink | 330000 µL | 330 mL |
| A wine bottle | 750000 µL | 750 mL |
| A bathtub | 150000000 µL | 150000 mL |
| An Olympic swimming pool | 2.5 × 1012 µL | 2.5 × 109 mL |
The microlitre is a unit of volume equal to one millionth of a litre, written µL. It is exactly one cubic millimetre. It is the working unit of the molecular biology laboratory and of clinical haematology, and almost every quantity in modern biological science that is not a mass or a concentration is a number of microlitres.
Pipetting is what defines it in practice. Adjustable micropipettes are named after their maximum volume in microlitres, so a bench holds instruments of 2, 20, 200 and 1000, and a researcher's day consists largely of moving microlitres from one tube to another. A polymerase chain reaction is typically assembled in twenty to fifty microlitres, and a whole experiment may use less liquid than a teaspoon holds.
Blood counts are reported against it. White cells number between four thousand and eleven thousand per microlitre in a healthy adult, platelets between a hundred and fifty thousand and four hundred thousand, and red cells about five million. Those reference ranges are among the most widely used numbers in medicine, and all of them are counts within a cube one millimetre on a side.
Diagnostics has driven the volumes down. A modern blood glucose meter needs about half a microlitre of blood, which is why a finger-prick sample is enough where an earlier generation of instruments needed a syringe. Point-of-care analysers, lateral flow tests and microfluidic cartridges are all designed around the smallest sample a patient can be asked to give.
Analytical chemistry uses the same scale. Injection volumes in liquid chromatography run from one to twenty microlitres, gas chromatography uses one or less, and mass spectrometry samples are prepared in tens. Because the analytical signal depends on the amount injected, the accuracy of a microlitre-scale measurement sets the accuracy of the whole result.
The identity with the cubic millimetre is a genuine convenience. Haematology once reported cell counts per cubic millimetre and now reports them per microlitre, and the numbers did not change at all, because the two units are the same. That is a rare case of a unit change in medicine that required no re-education and produced no errors.
One microlitre equals 1 cubic millimetre, 0.001 millilitres, 0.000001 litres, or about 0.0000338 US fluid ounces.
The millilitre is a unit of volume equal to one thousandth of a litre, written mL or ml. It is exactly one cubic centimetre. It is the working unit of medicine, cookery, cosmetics and the laboratory, and it is the smallest volume most people handle deliberately in the course of a day.
Medicine relies on it more heavily than on any other unit of volume. Oral liquids are dosed in millilitres, syringes are graduated in them, intravenous fluids are prescribed as so many millilitres per hour, and blood test results are reported per millilitre or per decilitre. The precision matters: a tenfold dosing error in a paediatric prescription is a difference of a single decimal place in this unit.
That is why the household spoon has been driven out of medical instructions. A teaspoon is nominally five millilitres, but real spoons vary from two to nine, so dosing devices are now supplied with liquid medicines and marked in millilitres. Regulators in several countries require the millilitre marking precisely because it removes an ambiguity that spoons cannot.
Cooking outside the United States runs on it. European and Asian recipes give liquids in millilitres and litres rather than in cups, which is more precise because a cup measures volume by an unstandardised container while a millilitre does not. Wine and spirit measures, coffee shot sizes, and the capacity of a baby bottle are all specified in millilitres.
A convenient identity helps in the kitchen and the laboratory alike. One millilitre of water has a mass of one gram, so a recipe or a protocol can move between mass and volume for water-like liquids without a real error. Cosmetics use the same unit throughout, from a five-millilitre sample to a five-hundred-millilitre bottle.
Against United States and imperial measures it converts awkwardly, and the two differ from each other. One millilitre is 0.0338 United States fluid ounces but 0.0352 imperial fluid ounces, so a fluid ounce is about four per cent larger in Britain than in America, and any drink or medicine volume converted between them needs to state which system was meant.
One millilitre equals 1 cubic centimetre, 0.001 litres, about 0.0338 US fluid ounces, or about 0.0352 imperial fluid ounces.