Conversion from Microliters to Centiliters

Information about the Microliter (µL)

The microlitre is a unit of volume equal to one millionth of a litre, written µL. It is exactly one cubic millimetre. It is the working unit of the molecular biology laboratory and of clinical haematology, and almost every quantity in modern biological science that is not a mass or a concentration is a number of microlitres.

Pipetting is what defines it in practice. Adjustable micropipettes are named after their maximum volume in microlitres, so a bench holds instruments of 2, 20, 200 and 1000, and a researcher's day consists largely of moving microlitres from one tube to another. A polymerase chain reaction is typically assembled in twenty to fifty microlitres, and a whole experiment may use less liquid than a teaspoon holds.

Blood counts are reported against it. White cells number between four thousand and eleven thousand per microlitre in a healthy adult, platelets between a hundred and fifty thousand and four hundred thousand, and red cells about five million. Those reference ranges are among the most widely used numbers in medicine, and all of them are counts within a cube one millimetre on a side.

Diagnostics has driven the volumes down. A modern blood glucose meter needs about half a microlitre of blood, which is why a finger-prick sample is enough where an earlier generation of instruments needed a syringe. Point-of-care analysers, lateral flow tests and microfluidic cartridges are all designed around the smallest sample a patient can be asked to give.

Analytical chemistry uses the same scale. Injection volumes in liquid chromatography run from one to twenty microlitres, gas chromatography uses one or less, and mass spectrometry samples are prepared in tens. Because the analytical signal depends on the amount injected, the accuracy of a microlitre-scale measurement sets the accuracy of the whole result.

The identity with the cubic millimetre is a genuine convenience. Haematology once reported cell counts per cubic millimetre and now reports them per microlitre, and the numbers did not change at all, because the two units are the same. That is a rare case of a unit change in medicine that required no re-education and produced no errors.

One microlitre equals 1 cubic millimetre, 0.001 millilitres, 0.000001 litres, or about 0.0000338 US fluid ounces.

Information about the Centiliter (cL)

The centilitre is a unit of volume equal to one hundredth of a litre, or ten millilitres. Its symbol is cL, and the lower-case cl is also used. Unlike most centi-prefixed units it has a real commercial life, because it happens to be the size that suits drink labelling, and in several countries it is the form printed on almost every bottle.

Drink containers are its main employment. In France, Belgium, Italy and Spain a wine bottle is labelled 75 cL, a beer 33 or 50 cL, a soft drink 33 cL, and a spirits miniature 5 cL. The same containers carry 750 ml and 330 ml in Britain, Germany and most of the English-speaking world, which is why identical bottles appear to bear different numbers depending on where they were filled.

Bar measures follow the same split. A standard spirit serving is 4 cL in France and 2 or 4 cL in Germany and Austria, while Britain pours 25 or 35 millilitres and the United States uses fluid ounces. European cocktail recipes are written in centilitres throughout, so a classic proportion of six parts to three to one appears as 6 cL, 3 cL and 1 cL, which reads more cleanly than the millilitre equivalents.

There is no legal difference between the forms. European Union labelling rules accept millilitres, centilitres and litres, so the choice is a matter of national typographic habit rather than of regulation. Where centilitres are used, the number on a bottle stays between one and a hundred for every ordinary container size, which is exactly the range a prefix is supposed to deliver.

The unit is also easy to picture. Ten millilitres is two teaspoons, a generous mouthful of water, or the dose measure supplied with a bottle of cough syrup. A tablespoon is one and a half centilitres, an espresso is about three, and a wine glass poured to a standard measure is twelve to fifteen.

Converting between systems needs some care because a centilitre falls between the two customary small measures. It is 0.338 United States fluid ounces and 0.352 imperial fluid ounces, so neither reads as a round number, and drink volumes converted between Europe and North America almost always end up rounded rather than exact.

One centilitre equals 10 millilitres, 0.01 litres, about 0.338 US fluid ounces, or about 0.352 imperial fluid ounces.