| Microliters (µL) | Cubic inches (in³) |
|---|---|
| 1 Microliter | 0.0000610237440947 in³ |
| 2 Microliters | 0.000122047488189 in³ |
| 3 Microliters | 0.000183071232284 in³ |
| 4 Microliters | 0.000244094976379 in³ |
| 5 Microliters | 0.000305118720474 in³ |
| 10 Microliters | 0.000610237440947 in³ |
| 20 Microliters | 0.00122047488189 in³ |
| 25 Microliters | 0.00152559360237 in³ |
| 50 Microliters | 0.00305118720474 in³ |
| 100 Microliters | 0.00610237440947 in³ |
| Reference | Microliters (µL) | Cubic inches (in³) |
|---|---|---|
| A teaspoon | 5000 µL | 0.305119 in³ |
| A can of soft drink | 330000 µL | 20.1378 in³ |
| A wine bottle | 750000 µL | 45.7678 in³ |
| A bathtub | 150000000 µL | 9153.56 in³ |
| An Olympic swimming pool | 2.5 × 1012 µL | 152559360 in³ |
The microlitre is a unit of volume equal to one millionth of a litre, written µL. It is exactly one cubic millimetre. It is the working unit of the molecular biology laboratory and of clinical haematology, and almost every quantity in modern biological science that is not a mass or a concentration is a number of microlitres.
Pipetting is what defines it in practice. Adjustable micropipettes are named after their maximum volume in microlitres, so a bench holds instruments of 2, 20, 200 and 1000, and a researcher's day consists largely of moving microlitres from one tube to another. A polymerase chain reaction is typically assembled in twenty to fifty microlitres, and a whole experiment may use less liquid than a teaspoon holds.
Blood counts are reported against it. White cells number between four thousand and eleven thousand per microlitre in a healthy adult, platelets between a hundred and fifty thousand and four hundred thousand, and red cells about five million. Those reference ranges are among the most widely used numbers in medicine, and all of them are counts within a cube one millimetre on a side.
Diagnostics has driven the volumes down. A modern blood glucose meter needs about half a microlitre of blood, which is why a finger-prick sample is enough where an earlier generation of instruments needed a syringe. Point-of-care analysers, lateral flow tests and microfluidic cartridges are all designed around the smallest sample a patient can be asked to give.
Analytical chemistry uses the same scale. Injection volumes in liquid chromatography run from one to twenty microlitres, gas chromatography uses one or less, and mass spectrometry samples are prepared in tens. Because the analytical signal depends on the amount injected, the accuracy of a microlitre-scale measurement sets the accuracy of the whole result.
The identity with the cubic millimetre is a genuine convenience. Haematology once reported cell counts per cubic millimetre and now reports them per microlitre, and the numbers did not change at all, because the two units are the same. That is a rare case of a unit change in medicine that required no re-education and produced no errors.
One microlitre equals 1 cubic millimetre, 0.001 millilitres, 0.000001 litres, or about 0.0000338 US fluid ounces.
The cubic inch is a unit of volume equal to 16.387064 cubic centimetres exactly. Its symbol is cu in, sometimes written in³. It is the volume of a cube one inch on each side, and 1728 of them make a cubic foot. Its most consequential role is legal rather than descriptive: the United States gallon is defined as exactly 231 cubic inches.
That definition is the reason American liquid measure is the shape it is. The figure of 231 comes from the English wine gallon standardised under Queen Anne in 1707, which the United States kept when Britain replaced its own gallons with a single imperial gallon in 1824. Every American fluid ounce, pint and quart descends from that one number, and it is why the two gallons differ by a fifth.
Engines made the unit famous. American car engines were quoted in cubic inches until the 1980s, and the numbers became names in their own right: a 350 is 5.7 litres, a 426 is 7.0, and a 302 is 4.9. Motorcycles still carry both figures, and the conversion is worth knowing, since 61 cubic inches make a litre.
Machinery uses it for swept volume. Pump and compressor displacement per revolution, hydraulic cylinder volume and metering pump strokes are all specified in cubic inches in American engineering, because the bores and strokes that produce them are already in inches and squaring or cubing an inch keeps the calculation in one system.
Freight pricing uses it in an unexpected way. American parcel carriers calculate a dimensional weight by dividing the package volume in cubic inches by a fixed divisor, commonly 139, to obtain a chargeable weight in pounds. A light bulky parcel is therefore priced by its cubic inches rather than by what it weighs, which changes how goods are packed.
The conversion to metric is exact but unhelpful. Because the inch is defined as exactly 2.54 centimetres, a cubic inch is exactly 16.387064 cubic centimetres, and no rounding is involved. That precision does not make the number easier to use, and it is the main reason engineering drawings outside the United States moved to millimetres.
One cubic inch equals 16.387 cubic centimetres, about 0.0164 litres, about 0.554 US fluid ounces, or 1/1728 of a cubic foot.