| Nanograms (ng) | Grams (g) |
|---|---|
| 1 Nanogram | 0.000000001 g |
| 2 Nanograms | 0.000000002 g |
| 3 Nanograms | 0.000000003 g |
| 4 Nanograms | 0.000000004 g |
| 5 Nanograms | 0.000000005 g |
| 10 Nanograms | 0.00000001 g |
| 20 Nanograms | 0.00000002 g |
| 25 Nanograms | 0.000000025 g |
| 50 Nanograms | 0.00000005 g |
| 100 Nanograms | 0.0000001 g |
| Reference | Nanograms (ng) | Grams (g) |
|---|---|---|
| A sheet of A4 paper (80 gsm) | 5 × 109 ng | 5 g |
| One litre of water | 1 × 1012 ng | 1000 g |
| Average adult human | 7 × 1013 ng | 70000 g |
| A small car | 1.4 × 1015 ng | 1400000 g |
The nanogram is a unit of mass equal to one billionth of a gram, or a thousandth of a microgram. Its symbol is ng. Expressed in the base unit of the SI it is 10 raised to the power minus twelve kilograms.
Nothing historical stands behind the nanogram. It exists because SI prefixes extend without limit, and it became useful only when instruments grew sensitive enough to justify it. A good analytical balance resolves tenths of a microgram and stops there; no balance weighs a nanogram directly. The quantity is instead inferred, from the signal a mass spectrometer, an immunoassay or a chromatography column produces when a known volume of sample passes through it.
Clinical laboratories are where most people meet the unit without noticing. Hormone and drug concentrations in blood are reported in nanograms per millilitre: testosterone, prostate-specific antigen, digoxin, tacrolimus, and vitamin D in American practice. Therapeutic drug monitoring depends on the scale, because the difference between an effective and a toxic concentration of some drugs is a few nanograms per millilitre. Anti-doping thresholds are written the same way, which is why an athlete can test positive for a substance present in quantities invisible by any other measure.
Environmental chemistry uses it for the most toxic contaminants, where the interesting concentrations are far below anything a gram-scale unit describes comfortably. Dioxins and furans in air are reported in nanograms per cubic metre, mercury and polycyclic aromatic hydrocarbons in nanograms per litre of water. Regulatory limits for these substances are set at concentrations that only became measurable in the second half of the twentieth century, so the unit and the regulation arrived together.
The scale is hard to picture. A single grain of fine table salt weighs roughly sixty micrograms, which is sixty thousand nanograms. A typical mammalian cell weighs on the order of one nanogram, so a nanogram of tissue is a handful of cells. A microgram of anything is already invisible; a nanogram is a thousandth of that.
One nanogram equals 0.001 micrograms, one millionth of a milligram, and one billionth of a gram.
The gram is a unit of mass equal to one thousandth of a kilogram. Its symbol is g. Although the kilogram is the SI base unit, the gram is the one that carries the prefixes, so milligram and microgram are built on the gram rather than on the kilogram.
That awkwardness is historical. The original metric system of 1795 defined the gramme as the mass of one cubic centimetre of water at the temperature of melting ice. It was intended as the base unit, but a one-gram standard is too light to be a practical reference: a speck of dust or a fingerprint changes it measurably. The thousandfold-larger kilogram was made the standard artefact instead, and the SI inherited the arrangement, leaving the base unit as the only one carrying a prefix in its own name.
Cooking outside the English-speaking world runs on grams, and increasingly inside it as well. Weighing flour rather than measuring it by volume removes the largest source of error in baking, because a cup of flour can vary by twenty per cent depending on how it was packed. Professional bakers work entirely in grams and express recipes as percentages of flour weight.
Nutrition panels report protein, fat, carbohydrate, sugar and fibre in grams, so the unit is the everyday currency of dietary arithmetic. Postal services price letters and small parcels in grams, and precious metals, though traded in troy ounces, are sold to the public in gram bars.
It is also the unit the SI prefixes attach to, which is why the system has a base unit that already carries a prefix. Smaller and larger masses are named from the gram and never from the kilogram: a thousandth of a gram is a milligram, not a microkilogram, and a million grams is a megagram, better known as the tonne. The rule spares the language a set of double prefixes that would otherwise be unavoidable, but it leaves the kilogram in the odd position of being the only base unit whose name contains one. Postal tariffs show the gram at work in ordinary life: letter rates step at 20, 50 and 100 grams, and a sheet of office paper weighs about five.
One gram equals 0.001 kilograms, one thousand milligrams, or about 0.035 ounces.